Oral Glucosamine Supplements as a Possible Ocular Hypertensive Agent

Radioiodine as a possible triggering agent for pemphigus foliaceus

Pemphigus foliaceus (PF) is an autoimmune blistering disease presenting in endemic and sporadic forms. The typical presentation is recurrent shallow erosions in a seborrheic distribution. PF has also been found in association with autoimmune diseases such as autoimmune thyroid disease (e.g. toxic nodular goiter and Hashimoto’s thyroiditis). In some patients, PF appears to be triggered by radioi...

Preparation of a 153Sm-5,10,15,20-tetrakis(4-methoxyphenyl) porphyrin complex as a possible therapeutic agent

Introduction: Porphyrins are interesting derivatives with low toxicity, tumor avidity and rapid wash-out suggested as potential radiopharmaceuticals in radiolabeled form. In this work we report, synthesis, radiolabeling, quality control, stability, partition coefficient determination and biodistribution studies of 153Sm-5,10,15,20-tetrakis(4-methoxyphenyl) porphyrin (153Sm-4-MPP) in ...

Propranolol as ocular hypotensive agent.

AHLQUIST (1948) suggested that adrenergic activity is divisible into alpha and beta groups. The former is concerned mainly with contraction of smooth muscle, including vasoconstriction in some areas-noradrenaline is almost exclusively an alpha substance. The latter includes adrenergic effects on the heart and relaxation of bronchial muscles-isoprenalin restricts itself almost entirely to such a...

Production and Evaluation of Lutetium-177 Maltolate as a Possible Therapeutic Agent

Production, Quality Control and Biological Evaluation of 166Ho-PDTMP as a Possible Bone Palliation Agent

Objective(s):In this study, 166Ho-1,2-propylene di-amino tetra(methy1enephosphonicAcid) (166Ho-PDTMP) complex  was prepared as a bone palliation agent. Materials and Methods:The complex was successfully prepared using an in-house synthesized EDTMP ligand and 166HoCl3. Ho-166 chloride was obtained by thermal neutron irradiation (1 × 1013 n.cm-2.s-1) of natural Ho(NO3)3 samples  followed by radio...